The aim of the work is a representation of the structure of on-going assessment of the functional state of highly skilled wrestlers in the dynamics of training process. Its main tasks are: diagnosis of psycho-physiological state of the athlete; assessment of the functional state of autonomic body systems; estimation and correction of the athlete’s psychological readiness; development and correction of individual training programs for the athletes’ preparation. Different cognitive strategies of perception and processing of information are examined in highly skilled wrestlers depending on functional asymmetry of the brain. The features of pre-start response in the manifestations of the neurodynamic functions and autonomic regulation of the heart rhythm are represented for highly skilled athletes in extreme competitive conditions. It is proposed a structural logic model of informative components of current diagnosis of the psychophysiological state of highly skilled wrestlers in the conditions of intense muscle and psycho-emotional activities.